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Monitoring urine colour (aiming for pale straw colour) provides a practical hydration indicator
There is currently no established pharmacological mechanism by which tirzepatide would be expected to cause or exacerbate RLS symptoms
In these cases, switching to semaglutide may be an option
Understanding that this valley is normal, documented, and temporary for most people is essential for maintaining the psychological resilience needed to continue treatment
The starting dosage of semaglutide is 0.25 once weekly, while the tirzepatide dosage starts at 2.5 mg once weekly
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