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Source: The Lancet, 2023 Cardiovascular outcomes in GLP-1 therapy Oral Delivery Improves Adherence Studies show that oral formulations of GLP-1 agonists achieve 15-25% higher adherence rates compared to weekly injections, leading to better long-term outcomes

BRIN-BD11 cells were used throughout this study for their well characterised responses to multiple stimuli, cell culture based convenience and their established intact response to GLP-1R activation both in terms of cAMP and resulting stimulated insulin secretion 36, 37

In addition, antioxidants that protect the liver from ROS damage and lipid peroxidation may be depleted: GSH, vitamin E, vitamin C and beta-carotene were found to be reduced in the NASH setting (38, 39)

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10.1089/aid.1996.12.1373 AIDS Res