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GLP-1 agonists typically delay gastric emptying, placing patients at an increased risk for aspiration upon induction if fasting times are not modified

Anandamide induces cough in conscious guinea-pigs through VR1 receptors

in the absence of validated data, a conservative approach is appropriate discard sooner rather than later if there is any doubt Lyophilised (unreconstituted) vials should be stored according to the supplier's or trial protocol's instructions

At rest, this translates to a modest heart rate elevation

But sibutramine is the documented precedent for exactly the kind of substitution that produces a cluster of unexplained organ injuries