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Hoyles L, Pontifex MG, Rodriguez-Ramiro I, Anis-Alavi MA, Jelane KS, Snelling T, et al

While the mechanistic insights are encouraging, further clinical investigations are needed to isolate the direct analgesic effects of GLP-1R agonists from those mediated by weight loss

As briefly mentioned before, repeated injections in the same spot can lead to tissue damage, irritation, lipohypertrophy, a condition where fatty lumps form under the skin, or lipoatrophy, a condition that causes fat loss resulting in dents under the skin

In conjunction with an appropriate diet and exercise regimen, GLP-1s can provide substantial health benefits to patients

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