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Subsequently, transmission electron microscope (TEM) observations showed that LPS treatment led to mitochondrial shrinkage, increased membrane density and reduced volume, and 2,3-cGAMP further aggravated this pathological change, while C-176 or GLP-1RAs could effectively alleviate the above-mentioned mitochondrial damage (Fig

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More studies are required to fully understand the underlying molecular mechanisms of MASLD-T2DM and search for specific treatment for high-risk patients

To view or add a comment, sign in A groundbreaking study has revealed that semaglutide, the active ingredient in popular weight-loss drugs like Wegovy and Ozempic, significantly reduces the risk of heart attack or stroke regardless of how much weight a person loses

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