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Innovative approaches, such as triphenylphosphonium derivative (TPT) nanoparticles, hyaluronic acid-coated particles, and polymeric nanovehicles, show promise in improving nanoparticle circulation time and tumor accumulation, enhancing therapeutic efficacy [334, 439,440,441,442,443]
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Sermorelin's plasma half-life is roughly 10 to 12 minutes in humans, consistent with rapid N-terminal cleavage by dipeptidyl peptidase IV (DPP-IV)
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