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The most frequently reported side effects typically include gastrointestinal symptoms such as nausea, vomiting, diarrhoea, and constipation, which affect a significant proportion of patients, particularly during dose escalation

Chemical derivatization-based LCMS/MS method for quantitation of gut microbial short-chain fatty acids

This study provides a novel perspective to improve our understanding of the mechanism of HUA-associated LVR and provides important information for pharmacological intervention