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In medical research, amylin signaling is linked to appetite control, feelings of fullness (satiety), and slower stomach emptying, which can reduce how quickly food leaves the stomach and may help limit meal size

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Symptoms of excessive intake appear at 5,0009,000 mg per day, an amount significantly higher than typical supplementation

While more human trials are needed to further explore this topic, one study showed depleted levels of glutathione in the hippocampus of generally healthy elderly persons, resulting in mild cognitive impairment, a precursor to more advanced impairment down the road