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10 REGARDLESS OF WHERE PLAQUE PsO MANIFESTS, IT IS OFTEN MORE THAN SKIN DEEP FOR PATIENTS 11,12 of patients with mild to moderate plaque psoriasis reported feeling embarrassed or self-conscious because of their skin 13, * of patients with mild to moderate disease perceived their severity to be worse than their affected BSA in the UPLIFT survey 14,, of psoriasis patients on therapy have cycled through 3 or more topicals and have not used an advanced therapy 15, RISK FACTORS OF DEVELOPING PSORIATIC ARTHRITIS INCLUDE: of patients with psoriasis are at risk of developing psoriatic arthritis 16 higher risk of developing psoriatic arthritis compared to patients without scalp involvement 17, ** higher risk of developing psoriatic arthritis compared to patients without nail involvement 17,** *According to a US cross-sectional survey conducted among 175 adult systemic-nave patients with mild to moderate plaque psoriasis (BSA 10%)

Some patients want to get pregnant and taking a GLP-1 could inhibit that process

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This was better than semaglutide alone (9.8%) and much better than liraglutide (6.2% in similar studies)

Anthocyanins suppress microglial activation and subsequent neuroinflammation