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When researchers tested pure GLP-1 receptor agonists, including semaglutide , liraglutide, and exenatide, none of them increased the beating rate of isolated heart tissue

I can tell you an example of a patient I saw yesterday that had lost significant weight and they were taking other medications And the dose had to be adjusted significantly because of their weight loss and they didnt know that. Patients on insulin, for instance, might need a lower dose as they shed pounds while using semaglutide

For severe cases, stem cell injections or other more invasive treatments may be more effective

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Coleman, R