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Chronic neuroprotection (Cerebrolysin ganglion cell survival) requires months to years as benefits accrue from preventing cell death that would otherwise occur

This DMF-upregulated DNA hydroxymethylation affects CBS locus chromatin structure modifications and upregulates gene expression

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For example, a doctor might prescribe the following: 100 micrograms daily for about a week Followed by every other day for seven doses After that, every three to four days for two to three weeks Once monthly until the deficiency is treated B12 injections require a prescription and can be administered at a doctor's office or at home with the approval of a healthcare provider