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A peptide is a chain of amino acids held together by peptide bonds, and those bonds are precisely what digestive enzymes (pepsin, trypsin) are built to cut, with the acidic stomach environment finishing the job so an oral peptide is largely destroyed before it can be absorbed, which is why injection is the default

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SYVN1 displayed the increased binding to GLUD1 following AdOx treatment, suggesting that SYVN1 may mediate the AdOx-induced GLUD1 ubiquitination (Fig