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In recent years, data have been accumulated suggesting effects of GLP-1 RAs on surrogate HF outcomes in HF patients across LVEF, including cardiac structure and function, exercise capacity and quality of life
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Semaglutide dosage follows a standard titration schedule starting at 0.25 mg weekly, increasing by 0.25 mg every four weeks until reaching a therapeutic dose of 0.52.4 mg
An important limitation also concerns potential selection bias
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