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Trial SURPASS-1 (Lancet 2021) Population 478 adults with T2D, monotherapy vs placebo

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Dose escalation timing Many researchers plateau because they have not yet reached their optimal dose

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The primary endpoint - MASH improvement absent fibrosis progression - was observed in 47%, 62%, and 43% of the 2.4, 4.8, and vs

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This hair loss pattern isn't unique to just medication-induced weight loss

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