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Enzymatic antioxidants are generally endogenous, although certain non-enzymatic antioxidants, such as coenzyme Q10, are also produced within the body

It occurs at the level of gene transcription [11, 12], epigenetic regulation [13,14,15], post-translational modifications of core and accessory cell death machinery components [16,17,18], organelle-specific mechanisms [19], and organelle crosstalk [20, 21]

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