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Hypoestrogenism, particularly of estriol, generates a group of symptoms known as the climacteric, which are characterized by vasomotor alterations, urogenital atrophy, and a series of metabolic changes, among other symptoms, which directly affect womens quality of life (Santoro and Randolph, 2011
[PMID: 20935547] PubMed record related to this compound for laboratory literature review
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