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The WHO: Officially validated GLP-1 receptor agonists (semaglutide, tirzepatide and liraglutide) as effective treatments for obesity in adults with a BMI of 30 or more

They consistently showed higher risk of mild to moderate gastrointestinal side effects in patients treated with GLP-1 receptor agonists

Boohaker RJ, Sambandam V, Segura I, Miller J, Suto M, Xu B

Nasal spray offers a middle ground with moderate bioavailability and no needles, though higher doses are required

$3,588 paid up front with no insurance Key Specs Accepts insurance: Yes Weight loss program included: Yes GLP-1 brand names offered: Ozempic, Zepbound, Mounjaro, Wegovy, Trulicity, Rybelsus, Saxenda, Victoza Type of GLP-1 available: Injectable and oral Cancel any time: No Found offers users a care team led by a physician specializing in weight loss