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demonstrated in KO mice that the regulation of -cell number and function by GLP-1 depends on the cAMP/PKA mediated-induction of insulin-like growth factor-1 receptor (IGF-1R) expression and the increased activity of insulin-like growth factor 2 (IGF-2)/IGF-1R by an autocrine mode of action [25]
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Unnikrishnan, R., Pradeepa, R., Joshi, S
It may slow down the progression of their disease and also their need to go on dialysis
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