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Head-to-head comparisons are limited, but existing data suggests GHK-Cu produces broader systemic effects while AHK-Cu may offer advantages in localized dermal applications

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This may provide a greater understanding of the role of G6PD in different pathological processes, and contribute to the development of rational therapeutic approaches for G6PD-associated diseases

Less severe but still problematic gastrointestinal reactions warrant dose holds and systematic side effect management