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If symptoms return before the next planned injection, seek clinical advice instead of changing the schedule yourself

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A recent meta-analysis of 12 observational studies found that higher dietary intake of vitamin B 12 was associated with a 23% lower risk of depression compared to lower intakes, but stratifying the data revealed a significant protective association in females, not in males (99)

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for this reason, some clinicians recommend an intradermal test dose in individuals who may be at risk of thiamine allergy