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In organotypic hippocampal slice cultures, Dihexa and Nle-AngIV similarly augmented spinogenesis, with control slices showing 7 spines per 50-m dendrite length, compared to 11 for both Dihexa and Nle-AngIV treated slices [2]

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In cardiac models, Bock-Marquette et al., Nature 2004 reported that T4 activates integrin-linked kinase and Akt signalling, promoting cardiomyocyte survival, migration and improved function after coronary ligation in mice