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Phase 2 trial in type 2 diabetes (Lancet 2023) also showed superior weight loss for the combination versus either monotherapy
It's rare to see noticeable change after that short time period with any product
Avoid exposure to extreme heat
Early warning signs of hypoglycemia may be less obvious in patients with hypoglycemia unawareness which can be due to a long history of diabetes (where deficiencies in the release or response to counter regulatory hormones exist), with autonomic neuropathy, intensified diabetes control, or taking beta-blockers, guanethidine, or reserpine
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