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While the combination therapy did not outperform the placebo, GLP-1 on its own showed a statistically significant improvement in liver scarring without worsening underlying liver inflammation, even among patients with the most advanced disease

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Intravenous administration of glutathione protects parenchymal and non-parenchymal liver cells against reperfusion injury following rat liver transplantation

It is believed that imbalanced gut microflora may contribute to CKD progression, but CKD also appears to disrupt the intestinal environment and affect microbiome composition