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reported in a propensity score-matched population-based cohort analysis that GLP-1 receptor agonist use in patients with MASLD and type 2 diabetes was associated with a lower risk of HCC (aHR: 0.55, 95%CI: 0.44-0.69) and all-cause mortality (aHR: 0.62, 95%CI: 0.55-0.71) [59]
Diabetes Obesity Metab 22:335345 Awad A, Madla CM, Mccoubrey LE, Ferraro F, Gavins FK, Buanz A, Gaisford S, Orlu M, Siepmann F, Siepmann J (2022) Clinical translation of advanced colonic drug delivery technologies
In HCC driven by obesity and nonalcoholic steatohepatitis, the downregulation of CPT2 leads to the accumulation of acylcarnitines, among which C18:1-carnitine enhances spheroid formation by HCC cells through STAT3 activation, indicating that the accumulation of acylcarnitine can promote the development of liver cancer [212]
The GHK-Cu peptide is extremely popular and very hard to find
It does not, by itself, establish that the dominant component is the intended GHK-Cu complex
