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In addition, the protective effects of both a recombinant adiponectin injection in ob/ob mice and metformin administration against NAFLD have been attributed, at least in part, to the inhibition of hepatic TNF expression 24,25

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Their results show that the availability of extracellular GSH can alter sensitivity to different treatments, or even confer resistance to drugs that block the uptake of these amino acids, with the implications that entails