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Cross-referencing with the UniProtKB database (50) and existing literature revealed a total of 11 proteins associated with histone or chromatin regulatory functions, visualized as a heat map (51) in Fig
It has also been suggested that repair of the 2nd strand takes advantage of the two-fold symmetry of many short-range complexes, such that its ligation is mediated by the second of the two ligase molecules that were present in the initial complex 12,15
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