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The microglial P2Y 6 receptor mediates neuronal loss and memory deficits in neurodegeneration
Both the FDA and European Medicines Agency reviewed the data and agreed there is no clear evidence of a risk right now
This works out to around 2.5 to 3.75 micrograms per kilogram of body weight for an 80kg adult, but as little as 1mcg/kg has been studied to provide benefits
In one study, 22 healthy women received 3 grams of MSM or a placebo per day for three weeks leading up to a half marathon
Longer term For longer protocols, review trends every 3-6 months with a clinician
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