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It is possible to hypothesize that activation of GIPR has the potential to protect from ischemic heart, given its similar effects on insulin production and myocardial Akt phosphorylation in mice and also a cardioprotective effect of ligargudide further supports this hypothesis [74]

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Preliminary controlled trials in depressed geriatric populations also suggest an antidepressant effect with acetyl-L-carnitine

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