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(2024) in db/db mice suggested superior efficacy in reducing inflammatory and fibrotic mediators, highlighting its potential in treating diabetic kidney disease

Nature 529 , 326335 (2016)

JACC Basic Transl Sci

In the current study, the exposure of the small intestine to metformin at different time intervals before the nutrient load was precisely controlled by direct infusion via a nasoduodenal catheter