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Wegovy (semaglutide) As of 2025, the out-of-pocket cost for Wegovy at CVS Pharmacy is typically around $1,350 to $1,500 per month without insurance
Note that this affects compounding pharmacies and has nothing to do with the FDA approving or clearing said peptides
Here is what most comparison articles will not tell you
Patients who haven't responded well to other GLP-1 medications, or who have a significant amount of weight to lose and want the strongest average efficacy available, are often good candidates for tirzepatide
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