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Although clinical trials specifically for MASH have not yet been conducted, preclinical studies confirm significant regulatory effects on hepatic metabolism, providing a novel strategy for targeted MASH therapy and supporting future translational research

These two phenomena must not be confused since weight loss is by the breakdown of fat cells and gain of muscle mass is by the upregulation of stem cells

Your body uses what it needs, and much of the excess is filtered out by the kidneys and passed in urine