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Molecular specifications Developer Code: LY3437943 Receptor Targets: GLP-1R, GIPR, GcgR (triple agonist) Molecular Weight: ~4,883 Da Half-life (in vivo): ~6 days (designed for weekly dosing in clinical studies) Form: Lyophilized powder Purity: 9899% The Three Receptors: What Each One Does Each of retatrutide's three target receptors produces distinct biological effects GLP-1R drives insulin secretion and appetite suppression, GIPR enhances insulin sensitivity and adipose effects, and GcgR increases energy expenditure through thermogenesis and fat oxidation