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Using advanced organic synthesis and biochemical technologies, we develop efficient, scalable synthetic routes and optimize reaction conditions and purification processes to ensure linker stability under physiological conditions and efficient cleavage in acidic environments

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This correlation was lost upon reoxygenation, however, as the NADP pool was rapidly reduced, while both Grx1-roGFP2 and roGFP2-Orp1 reported a burst in oxidation (Fig