glp-1 for mcas Not all GLP-1s work the same way MCAS. Most patients do better on Tirzepatide, the dual incretin with both and GIP receptor agonists. But some mast cells just respond better Peptides and Mast Cell Activation:

ATTAIN-1 compared Foundayo to placebo, and found that patients lost approximately 11% of their bodyweight on the highest Foundayo doses

Upper limit of the 95% CI (-0.19

Weiss G

Ongoing use of GLP-1 RAs may be limited by issues related to tolerability, efficacy, access, and cost. The boom in GLP-1 RAs has not gone unnoticed as this class of medication increased 300% from 2020 to 2022 and 3 different types of GLP-1 RAs have been under a drug shortage since 2024

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