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In CNS, GIP-R is expressed on the surface of cells both alone and in association with GLP1-R (60), acting on the same cells (facilitating GLP-1 internalization to specific neuronal populations (61)) or, as documented in other studies, on different cells (62)
Disruption of its function has been shown to have major impacts on mitochondrial integrity and cell survival (Halestrap et al., 2002
Exacerbation of alcohol-induced oxidative stress in rats by polyunsaturated Fatty acids and iron load
Therefore, it is more beneficial to consume these foods raw or lightly steamed if possible
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