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In addition to participating in detoxification reactions, NADPH is involved in the synthesis of lipids and proteins 71 , and in mice the retina fully matures until about PN30 72 during which time it needs to sustain a high level of lipid and protein production 73
Tirzepatide's dual action on GIP and GLP-1 receptors leads to significant metabolic changes, including alterations in blood glucose levels, fluid balance, and gastrointestinal functionall of which can potentially influence headache occurrence
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