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Combined hypothesis of migration synergy: If BPC-157 favors the transcriptional and signaling environment that enables migration and survival, while TB-500 favors actin-associated motility and the physical execution of movement, co-administration could increase both (1) the number of functional cells and (2) the efficiency with which they reach the injury site and organize the repair matrix
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In fact, the k cat / K m of SQOR toward H 2 S was estimated to be of the order of 10 7 M -1 s -1 ( 7 -fold higher than the rate constant for sulfide addition to disulfide in solution at pH 7.4 and 25 C (0.6 M -1 s -1 ) ( In the proposed catalytic cycle, sulfide first attacks the trisulfide bridge of the enzyme, generating persulfides at both Cys201 and Cys379
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