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The gastrointestinal side-effect profile of retatrutide observed in phase 2 trials is broadly consistent with other GLP-1-based therapies, such as semaglutide (Wegovy/Ozempic) and tirzepatide (Mounjaro), though retatrutide's additional glucagon receptor activity means its full profile may differ in ways that phase 3 data will clarify
If a risk cant be ruled out, the treatment isnt recommended
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[PMID: 14017791] PubMed record related to this compound for laboratory literature review
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