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iScience 26:105717 Kriston L, von Wolff A, Westphal A, Holzel LP, Harter M (2014) Efficacy and acceptability of acute treatments for persistent depressive disorder: a network meta-analysis

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If you suffer from mild depression once in a while, you can try a B12 shot as a mood booster some people have reported feeling happily giddy afterwards, but not for long

doi: 10.1155/2018/2930251 220 ZhouYCFangWHKaoTWWangCCChangYWPengTCet al

35 Two similar trials, each including 109 perimenopausal women, found that 4 mg of Siberian rhubarb extract daily reduced hot flashes, anxiety symptoms, and total menopausal symptom scores, and improved overall health and well-being more effectively than placebo after 12 weeks