semaglutide nash phase 3 2·4 mg once weekly in patients with non-alcoholic steatohepatitis-related cirrhosis: a randomised, placebo-controlled 2 trial Semaglutide Significantly Improves Steatohepatitis, Fibrosis

Theratechnologies / GlobeNewswire (FDA action) (2025) 3

In the STEP and SURMOUNT trials for semaglutide and tirzepatide respectively, weight loss curves generally began to flatten between weeks 36 and 60, reflecting the physiological set point adaptation that occurs as appetite suppression becomes partially offset by metabolic adaptation

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Its also essential to get enough sleep and manage stress through relaxation techniques like meditation or yoga