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These medicines include semaglutide (marketed as Ozempic for diabetes and Wegovy for weight management), liraglutide (Saxenda for weight management, Victoza for diabetes), dulaglutide (Trulicity for diabetes), and tirzepatide (Mounjaro for diabetes), which combines GLP-1 with glucose-dependent insulinotropic polypeptide (GIP) receptor agonism

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In preclinical studies, it has been estimated that about 20% of the total energy needs of the adult brain may be met by fatty acid oxidation occurring in astrocytes [33]