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Of a 12,000 mg dose, only 16% (1,920 mg) is absorbed, with all that excess causing some major gastric distress when it leaves the body

Graham Lipkin, Consultant Nephrologist at Queen Elizabeth Hospital Birmingham, "Those who take tacrolimus/ciclosporin should have their levels checked." This additional monitoring is crucial when initiating GLP-1 therapy due to the potential for drug interactions

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