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Contraindications MOTS-C peptide therapy may not be suitable for individuals who: Are pregnant or breastfeeding Are children or adolescents Have active cancer or neoplastic conditions Have severe liver or kidney disease Have autoimmune disorders requiring careful metabolic regulation Are using insulin or oral hypoglycemic medications due to hypoglycemia risk A full medical consultation is required prior to initiating therapy
The Coviello 2005 dose-response trial confirmed that low doses maintain intratesticular testosterone, though brand-name pricing after the 2020 compounding ban remains a real barrier
The peptide occurs naturally as part of thymosin beta-4, present in virtually all human and animal cells
Instead, it functions as a bacteriostatic agent
Neither is better
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