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Los estudios de farmacologa de receptores in vitro en modelos de clulas hipofisarias han examinado sus caractersticas de unin al receptor GHS-R1a, y las investigaciones publicadas documentan la activacin de la va de sealizacin relacionada con la GH sin estimulacin simultnea de la hormona adrenocorticotrpica (ACTH) ni liberacin de cortisol en paneles comparativos de secretagogos que incluyen GHRP-6 y GHRP-2 [1]
For individuals with pre-existing gastrointestinal conditions such as inflammatory bowel disease, previous bowel surgery, or chronic constipation, closer monitoring may be warranted when initiating therapy
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