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Treatment of B6 mice with the GLS1 inhibitor BPTES significantly reduced histological scores in the spinal cord of affected animals, lowered the number of CD4 + T cells, IL-17A and IFN-producing CD4 + T cells in the spinal cord, substantially decreased clinical scores and weight loss, and ameliorated experimental autoimmune encephalomyelitis (47)

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Participants could be discontinued for serious adverse events, withdrawal of consent, or clinician judgment of unacceptable risk

The global supply chain has been impacted, resulting in delayed deliveries at present time

Anaerobe 14(1):4348