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Over 26 weeks, including a dose-escalation period of up to 6 weeks, researchers observed mean percentage weight reductions of 6.0% to 10.8% across the cagrilintide dose groups compared to just 3.0% with placebo

In addition, a study of about 3,000 American adults aged 40 and over found that people with higher blood selenium levels also tended to have higher bone mineral density in parts of the skeleton like the spine and femur, and they had lower risk scores for fractures

Zhang AQ, Mitchell SC, Smith RL

2022;71: Altimmune Announces Positive Topline Results from MOMENTUM 48-Week Phase 2 Obesity Trial of Pemvidutide Altimmune

However, some drug development was attempted, albeit unsuccessfully