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MOTS-C MOTS-C may boost metabolism and promote muscle repair

This parameter has been further studied, showing that those men and women in the lowest quartile of the IGF-1/IGFBP3 ratio are threefold more likely to meet the Adult Treatment Panel III (ATP-III) definition for MetS, and twice as likely to be insulin resistantthat IGF-1/IGFBP-3 ratio decreases notably as the number of MetS components increases [217]

That is exactly why it stacks so neatly with an incretin compound rather than duplicating it

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This may be advantageous in severe cases of mitochondrial diseases where there could be insufficient ATP available to synthesize glutathione from GGC