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The mechanism seems to be independent of the catalytic activity, since these effects were not mimicked by systemic DPP-4 inhibition (73, 82), and it was suggested that soluble DPP-4 interacted with caveolin-1 on adipose tissue macrophages, the down-stream effects of which combined with actions of other pro-inflammatory molecules such as factor Xa, to lead to activation of the inflammatory signaling pathway (83) (Figure 3)

Results often last up to a year

Gathering everything before starting prevents mid-process interruptions that leave vials exposed to air or temperature fluctuations

The injection process is straightforward and most patients become comfortable self-administering at home after their initial guidance from their Wave Aesthetics provider