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Notably, the AKT pathway governs histone acetylation: AKT inhibition reduces H3/H4 acetylation marks and suppresses ADM in Kras-mutant cells, with Kras driving acetylation via AKT signaling [389]
Your healthcare provider will start the initial dose at a lower level
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Fan C, Lin B, Huang Z, Cui D, Zhu M, Ma Z, et al
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