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Semaglutide and tirzepatide partially mitigated this decline, whereas PG-102 more effectively preserved body weight, countering the metabolic deterioration (Fig

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The cumulative incidence was 6.7% for semaglutide versus 0.8% for the non-GLP-1 RA group over 36 months

The patent estate is a core input to the DCF model, and the due diligence process must include a comprehensive analysis of patent validity risk, LOE timing probability distributions, and competitive biosimilar or generic development timelines